the association between sporadic alzheimer’s disease and the human abca1 and apoe gene polymorphisms in iranian population

نویسندگان

hr khorram khorshid genetic research centre, university of social welfare and rehabilitation sciences, iran +98-21-22180138, [email protected]; genetic research centre, university of social welfare and rehabilitation sciences, iran +98-21-22180138, [email protected]

e gozalpour genetic research centre, university of social welfare and rehabilitation sciences, iran

k kamali genetic research centre, university of social welfare and rehabilitation sciences, iran

m ohadi genetic research centre, university of social welfare and rehabilitation sciences, iran

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The Association between Sporadic Alzheimer’s Disease and the Human ABCA1 and APOE Gene Polymorphisms in Iranian Population

BACKGROUND Apolipoprotein E (APOE), which its ε4 allele has been reported as a risk factor in late onset Alzheimer's disease (AD), is the main cholesterol carrier in the brain. ATP-binding cassette transporter A1 (ABCA1) gene on chromosome 9, which has been known by genome-wide AD linkage study, has an important role in cellular cholesterol efflux. This study determines the association between ...

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عنوان ژورنال:
iranian red crescent medical journal

جلد ۱۳، شماره ۴، صفحات ۲۵۶-۲۶۲

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